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GEICAM/2003-08_MAP3

A phase III randomized study of Exemestane versus placebo in postmenopausal women at increased risk of developing Breast Cancer

Medical Coordinator:

Dr. José Enrique Alés Martínez

Sponsor:

GEICAM

Included Patients:

432

Link:

Not available

+ Publications in Scientific Journals - Publications in Scientific Journals
  • Clinical Breast Cancer
    Goss PE, Richardson H, Chlebowski R, Johnston D, Sarto GE, Maunsell E, Ingle JN, Alés- Martinez JE. National Cancer Institute of Canada Clinical Trials Group MAP.3 Trial: evaluation of exemestane to prevent breast cancer in postmenopausal women. Clinical Breast Cancer, 2007 Dec; 7(11):895-900. DOI:
    http://dx.doi.org/10.3816/CBC.2007.n.057 http://www.clinical-breast-cancer.com/article/S1526-8209(11)70794-7/abstract.
  • New England Journal of Medicine
    Goss PE, Ingle JN, Alés-Martínez JE, Cheung AM, Chlebowski RT, Wactawski-Wende J, McTiernan A, Robbins J, Johnson KC, Martin LW, Winquist E, Sarto GE, Garber JE, Fabian CJ, Pujol P, Maunsell E, Farmer P, Gelmon KA, Tu D, Richardson H; the NCIC CTG MAP.3 Study Investigators. Exemestane for Breast-Cancer Prevention in Postmenopausal Women. N Engl J Med. 2011 Jun 23;364(25):2381-91. Epub 2011 Jun 4.
    https://www.ncbi.nlm.nih.gov/pubmed/21639806.
  • Journal of Clinical Oncology
    Maunsell E, Goss PE, Chlebowski RT, Ingle JN, Alés-Martínez JE, Sarto GE, Fabian CJ, Pujol P, Ruiz A, Cooke AL, Hendrix S, Thayer DW, Rowland KM, Dubé P, Spadafora S, Pruthi S, Lickley L, Ellard SL, Cheung AM, Wactawski-Wende J, Gelmon KA, Johnston D, Hiltz A, Brundage M, Pater JL, Tu D, Richardson H. Quality of life in MAP.3 (Mammary Prevention 3): a randomized, placebo-controlled trial evaluating exemestane for prevention of breast cancer. J Clin Oncol. 2014 May 10;32(14):1427-36. doi: 10.1200/JCO.2013.51.2483. Epub 2014 Apr 7.
    https://www.ncbi.nlm.nih.gov/pubmed/24711552.

+ Congress Communications - Congress Communications
  • Poster en Simposio SEOM 2010
    Robles Díaz L, Valdivieso N, Piñas N, Cortés-Funes F, Cortés-Funes H. Preferencias en cuanto a quimioprevención en mujeres postmenopáusicas con riesgo aumentado de cáncer de mama. I Congreso Nacional SEOM. 27-29 Octubre, 2010. Madrid.
  • Comunicación oral en ASCO 2011
    Goss P, Ingle J, Alés-Martínez JE, Man-Wei-Cheung A, Chlebowsie L, Wactawski-Wende J, McTiernan A, Robbins J, Johnson K, Martin L, Winquist E, Sarto G, Garber J, Fabian C, Pujol P, Maunsell E, Farmer P, Gelmon K, Tu D, Richardson H. Exemestane for primary prevention of breast cancer in postmenopausal women: NCIC CTG MAP.3—A randomized, placebo-controlled clinical trial. 47th American Society Clinical Oncology Annual Meeting. 3-7 Junio, 2011. Chicago. USA. J Clin Oncol 29: 2011 (suppl; abstr LBA504)
    http://ascopubs.org/doi/abs/10.1200/jco.2011.29.18_suppl.lba504.
  • Poster en SEOM 2011
    Ales Martínez JE, Ruiz A, Richarsond H, Chacón JI, Lluch A, Ramos M, Córdoba O, Aguirre E, LeMaitre A, Goss P. MAP.3/EXCEL/GEICAM2003-08. Estudio aleatorizado de exemestano controlado con placebo en prevención primaria de cáncer de mama en mujeres posmenopáusicas: resultados en la cohorte española. XIII Congreso Nacional SEOM. 19-21 Octubre, 2011. Málaga.
  • Comunicación oral en SABCS 2011
    Maunsell E, Richardson H, Ingle JN, Ales-Martinez JE, Chlebowski RT, Fabian CJ, Sarto GE, Garber JE, Pujol P, Hiltz A, Tu D, Goss PE. Menopause-specific and health-related qualities of life among post-menopausal women taking exemestane for prevention of breast cancer: results from the NCIC CTG MAP.3 placebo-controlled randomized controlled trial. 34th Annual San Antonio Breast Cancer Symposium. 6-10 Diciembre, 2011. San Antonio. USA.
    http://cancerres.aacrjournals.org/content/71/24_Supplement/S6-1.
  • Poster en SABCS 2011
    Goss P, Richardson H, Chavarri-Guerra Y, Chlebowski R, Ingle J, Ales-Martinez J, Fabian C, Sarto G, Garbe J, Pujol P, Maunsell E, Hilts A, Tu D, Cheung A. The influence of two years of exemestane on bone mineral density in postmenopausal women at increased risk of developing breast cancer - A companion study to MAP.3. 34th Annual San Antonio Breast Cancer Symposium. 6-10 Diciembre, 2011. San Antonio. USA.
    http://cancerres.aacrjournals.org/content/71/24_Supplement/P4-11-13.


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